In addition, our study also demonstrated that miR-377-3p could reverse the favorable effects of NEAT1 on cell growth, metastasis and negative role of NEAT1 on cell apoptosis in NSCLC cell lines, which demonstrated NEAT1 played its favorable role on NSCLC progression, at least in part, through inhibition of miR-377-3p. This evidence concerns the gene NEAT1 and non-small cell lung carcinoma.