18F-Alfatide PET and 18F-FDG PET imaging were interrelated in tumor detection; SUVFDG, SUVRGD, GLUT-1, and αvβ3 in tumors were correlated closely with each other, and the spatial heterogeneity of SUVFDG in different tumor layers was consistent with SUVRGD in rough calculation. The gene discussed is SLC2A1; the disease is neoplasm.