All tumours presented cytoplasmic and membranous Ephrin-B2 expression in 25 to 90% of the tumour cells, as well as neurons, inflammatory cells and vascular endothelial cells, as reported (Gale et al., 2001; Sawamiphak et al., 2010; Ottone et al., 2014). Here, EFNB2 is linked to neoplasm.