It is to be noted that CXCR3 is the cognate receptor of the chemotactic ligands CXCL9 and CXCL11 in addition to CXCL10; these chemokines may have some redundant effect with CXCL1038, and explain the more significant attenuation of the FFC diet-induced NASH in the CXCR3−/− mice when compared to the CXCL10−/− mice. Here, CXCR3 is linked to metabolic dysfunction-associated steatohepatitis.