As can be seen in Fig. 4, somewhat similar CRAd-IL24 and control CRAd progeny titers were detected in OVCAR3 and OV-4 cells while CRAd-IL24 infection of SKOV3ip.1 and SKOV3luc cells resulted in significantly increased titers of infectious progeny as compared to control CRAd. The gene discussed is IL24; the disease is infection.