Three typical cell lines of pancreatic cancer (PANC 1, MIA PaCa-2, and Capan-1) and one subline established in our laboratory (Capan-1 M9 [10], see 3.2) showed positive staining with anti-SHH and anti-GLI1 antibodies (Fig. 1). The gene discussed is GLI1; the disease is familial pancreatic carcinoma.