These miRNAs affect posttranscriptional regulation of target proteins in HCC cells, in particular inducing decreased expression levels of stathmin-1 (STMN1) and insulin-like growth factor-1 receptor (IGF-R1), and, importantly, inhibiting proliferation of cancerous cells in in vitro experiments [172]. This evidence concerns the gene STMN1 and hepatocellular carcinoma.