In the same direction, miR-126/126* pair has been shown to have an antitumor role by inhibiting breast cancer cell invasion and metastasis [100], either through the direct targeting of stromal cell-derived factor-1 alpha, SDF-1α, and with the indirect suppression of chemokine (C-C motif) ligand 2, CCL2, in cancer cells. This evidence concerns the gene CCL2 and breast carcinoma.