Annexin-V/PI double staining indicated that EGCG at a concentration of 50 and 100 μM significantly induced apoptosis in HCC-LM3 cells (32.28%, 39.37% vs. 8.33%, P = 0.048, P = 0.0091, respectively) and HepG2 cells (39.60%, 57.18% vs. 3.07%, P = 0.013, P = 0.0016, respectively), albeit to varying degrees (Fig. 3C). Here, ANXA5 is linked to hepatocellular carcinoma.