Analysis of the potential effect of EGCG on other glycolytic proteins showed that at a dose of 50 μM, EGCG down-regulated the protein expression of GLUT2 in HCC-LM3 and HepG2 cells (Fig. 2E), suggesting that EGCG may inhibit glycolysis at a broad level in aerobic glycolytic HCC cells. The gene discussed is SLC2A2; the disease is hepatocellular carcinoma.