According to recent studies, it has demonstrated a positive effect of RIPC on endothelial dysfunction, i.e., improving flow-mediated vasodilatation [34], increasing immunoreactivity of vasodilatative NO synthase [35], upregulating NO [36], increasing of endothelium progenitor cells [37] and vascular endothelial growth factor expression [38]. This evidence concerns the gene VEGFA and endothelial dysfunction.