We divided MYC translocation positive DLBCL into the following subgroups according to TP53 mutation and BCL2 translocation status: MYC/BCL2 double translocation with TP53 mutation, MYC single translocation with TP53 mutation, MYC/BCL2 double translocation, and isolated MYC translocation. The gene discussed is TP53; the disease is diffuse large B-cell lymphoma.