However, this region is homologous with regions of two human proteins that regulate lipid metabolism: cytoplasmic retinoic-acid binding protein-1 (CRABP-1) and low density lipoprotein-receptor-related protein (LRP) [16], which would result in increased apoptosis of peripheral adipocytes, decreased pre-adipocyte differentiation, decreased triglyceride storage in adipose tissue, increased VLDL production, impaired hepatic chylomicron uptake and endothelial triglyceride clearance, resulting in hypertriglyceridaemia [16, 32]. Here, CRABP1 is linked to hypertriglyceridemia.