F6P (Fructose-6-phosphate) in Huh7 cells expressing S351E tended to decrease, whereas the UDP-GlcNAc (UDP-N-acetylglucosamine) increased (Supplementary Table 1), raising a possibility that the hexosamine pathway is also enhanced by the p62–Keap1–Nrf2 axis and involved in tumour development. The gene discussed is NFE2L2; the disease is neoplasm.