TWIST1 and skin cancer: p62 has been recently reported to exert a role in controlling mitosis transition through CDK1-mediated phosphorylation at Threonine 269 (T269) and Serine 272 (S272).47 p62 can bind to and inhibit Twist-1 autophagic degradation, thus promoting xenografted human skin cancer cell growth in a Twist-dependent manner.48 In our study, we performed BrdU, cell-cycle and apoptosis assays to investigate whether the effects of p62 arisen from its influence on cell short-term proliferation and viability.