In this study, we identified a list of miRNA candidates affected by knockdown of DDX3 (Table 2) and verified the expressions of tumor-suppressive miR-145, miR-200b, miR-200c and miR-122, but not miR-10b and miR-519a, positively correlated with DDX3 level in HCC clinical samples (Fig. 5a–f). This evidence concerns the gene DDX3X and neoplasm.