In another study carried out over 16 weeks in 52 individuals with obesity, insulin resistance and suspected NAFLD, a normal carbohydrate (60% carbohydrate, 25% fat, 15% protein) or moderately restricted carbohydrate (40% carbohydrate, 45% fat, 15% protein) diet again resulted in a similar decrease in body weight, daily insulin requirement and plasma liver enzymes levels. This evidence concerns the gene INS and Obesity.