Unexpectedly, we found that constitutive activation of TGFBR1 using GLI-Kruppel family member GLI1 (Gli1)-CreERT2 (designated as TGFBR1-CAGcre; Figure S7A) caused the development of INHA-positive ovarian tumors following tamoxifen injection (Figure S7B-H). The gene discussed is TGFBR1; the disease is ovarian neoplasm.