RIPK3 transcript was significantly reduced in CRC when compared with NC tissues in seven out of eight datasets including TCGA Colorectal (NC/CRC=22/215); Skrzypczak Colorectal (24/45); Skrzypczak Colorectal 2 (20/20); Sabates-Bellver Colon (32/25); Gaedcke Colorectal (65/65); Hong Colorectal (12/70); and Kaiser Colon (5/100) (Figure 7A). This evidence concerns the gene RIPK3 and colorectal carcinoma.