SDCBP and cancer: The primary direction of research on MDA-9/Syntenin (SDCBP) in cancer over the past two decades focused on defining its role in the context of tumor cells from different organ sites (7-11, 30,31,33,45,52,53) Although expression is significantly lower in normal vs. transformed cells, the MDA-9/Syntenin protein is ubiquitously expressed in the mouse (in both developing and adult stages [28, 51]) and in adult human organs, e.g., skin, liver, gall bladder, colon (www.Proteinatlas.org).