In contrast, the monocytic CD11b+Gr1dim splenocyte fraction (Figure 5D) displayed a reproducible and remarkable potential for tumor cell eradication if reexposed in vitro to either CpG alone (Figure 5, image 6 vs 10 ***p < 0.0001 and Supplemental Figure S5, image 6 vs 10 ***p < 0.0001) or to CpG+IFNγ (Figure 5, image 11 vs 15 ***p < 0.0001 and Supplemental Figure S5, image 16 vs 20 ***p < 0.0001). The gene discussed is IFNG; the disease is neoplasm.