In contrast, CD11b+Gr1+ host myeloid cells remained the dominant host constituent in the regressing tumors of CY+CpG-treated 4T1-bearing mice (Figure 4) and, as importantly, CD11b+Gr1dim cells from CY+TLRa treated TB or even naïve mice became highly tumoricidal upon in vitro reexposure to exogenous CpG, with the tumoricidal state extending to 7 days if reexposure to IFNγ was also included (Figures 5, 6, 7). The gene discussed is IFNG; the disease is tuberculosis.