CD11b+Gr1dim splenocytes from CY+CpG-treated 4T1 TB mice required only in vitro reexposure to CpG to inhibit both 4T1 and CT26 tumor cells, while sparing non-transformed mouse 3T3 fibroblasts (Figure 5 and data not shown). The gene discussed is ITGAM; the disease is neoplasm.