HOTAIR and breast cancer: In addition to breast cancer, overexpression of HOTAIR has been reported to be a marker for poor prognosis in various cancer types [61], including gastro-intestinal cancers [62, 63, 64, 65], urologic cancers [66, 67], gynecologic cancers [68, 69, 70], lung cancers [71, 72] and undifferentiated carcinoma of nasopharyngeal type [73].