We found greater expression of Fgf2, β3 integrin and Cdx4 mRNA in the low-Hox group versus control, but expression in the high-Hox group was significantly greater than control or low-Hox groups (p<0.0001 for all comparisons, n=3 control samples and n=6 AML samples) (Figure 7A). Here, FGF2 is linked to acute myeloid leukemia.