To further validate microarray results, we analyzed EIF3H expression using qRT-PCR and Western blot in 40 pairs of predominately HBV-related HCC and the corresponding peri-tumoral tissues (Supplementary Table 5, cohort 1 and Figure 1B1 and 1B2), and found that EIF3H was significantly up-regulated (P=0.006) in HCC (Figure 1A3). Here, EIF3H is linked to hepatocellular carcinoma.