The expression level of SFMBT2 was high in normal RWPE-1 prostate cells and poorly metastatic LNCaP prostate cancer cells, but low in highly metastatic prostate cancer cells, such as PC3 and DU145, indicating that SFMBT2 expression is likely related to metastasis (Figure 1A). Here, SFMBT2 is linked to Familial prostate cancer.