Of interest, histology of the pancreas of CFTRΔF508/ΔF508 pigs was less severe than the CFTR−/− pigs [87] indicating that minimal CFTR presence/function in ΔF508 pigs may reduce pancreatic disease progression, an important finding which may facilitate researchers in understanding pancreatic disease development and progression in CF individuals. Here, CFTR is linked to cystic fibrosis.