However, it is important to note that because of the dual role played by TGFβ, acting as both tumor suppressor and tumor promoter, elucidation of the molecular events and components leading to both arms of TGFβ signaling will be critical to further design therapeutic strategies aimed at specifically blocking TGFβ-mediated tumor metastasis without affecting the tumor suppressive effects of this growth factor. Here, TGFB1 is linked to neoplasm.