PRDM16 and gestational diabetes: In concordance with the analyses of the continuous glycemic traits, BMP7 and PRDM16 DNA methylation levels were lower in placenta exposed to GDM as compared to those not exposed (BMP7 mean: 27.4 ± 4.8 vs. 29.9 ± 6.9; p = 0.03 and PRDM16 - CpG3; 38.8 ± 15.6 vs. 43.8 ± 13.7, p = 0.08) (Table 3).