Various strategies have been envisaged to block the expression or function of Survivin in tumour cells (i) immunotherapeutic approaches to induce immune response against Survivin, (ii) small molecule inhibitors/antagonists to block function of Survivin, (iii) nucleic acid based approaches which interfere with Survivin gene expression or (iv) gene ablation of Survivin to regulate cell cycle and apoptosis. Here, BIRC5 is linked to neoplasm.