Three previous studies have shown a high expression of this miRNA in CpG island methylator‐phenotype positive or TP53‐mutated colon tumours 37, human periodontal ligament‐derived stem cells derived from smokers 34 and a lower expression in systemic lupus erythematosus and rheumatoid arthritis patient cells 38. This evidence concerns the gene TP53 and colonic neoplasm.