Considering the roles of TLR4, IL-17 and miR-146a in the pro-inflammatory response12, we conducted a population-based case control study in a Chinese Han population, with the goals of exploring whether genetic polymorphisms in IL-17, TLR4, and miR-146a are associated with susceptibility to and the prognosis of pulmonary tuberculosis. This evidence concerns the gene TLR4 and pulmonary tuberculosis.