MAIT cells were readily and specifically activated in response to DENV-treated APCs (multiplicity of infection (MOI)=1), as indicated by production of IFN-γ and Granzyme B (Fig. 3a,b), as well as, expression of CD38, with minimal production of TNF-α (Supplementary Fig. 1a–c). The gene discussed is IFNG; the disease is infection.