INS and colorectal carcinoma: A high rate of digestion of refined grains and the consequent increases in plasma insulin and insulin-like growth factor 1 have been related to an increased risk of CRC.[56,57] Furthermore, a meta-analysis indicated that a high intake of milk with a relative risk (RR) of 0.83 (95% CI = 0.74–0.93) and a high intake of total dairy products with a RR of 0.81 (95% CI = 0.74–0.90) were associated with reductions in CRC risk compared with low intake of these foods.[12]