CCL2 and infection: In the MBEC monolayer model, the infection with D4MB-6 induced changes in PECAM and VCAM transcription at 2 h p.i. (1.5 fold and 96 fold, respectively), whereas at 10 h p.i., there was a reduction in the transcription of the same molecules (0.2-fold and 17-fold, respectively), but the MCP-1 messenger was up-regulated (almost 4000-fold).