RPS14 and cytomegalovirus infection: The observed lack of activity of emetine against HCMV and MCMV in low-density as compared to high-density cells (Fig 4), and a previous study that correlated emetine resistance in Chinese hamster ovary cells with mutations in RPS14 [30], prompted us to investigate the functional role of RPS14 in HCMV infection and emetine treatment (summary model, Fig 11).