Mean serum NT-proBNP was not statistically different between the two groups (1191.3 pg/mL in cirrhotics versus 567.3 pg/mL in malignancy, P = 0.16); however, in the cirrhotic cohort, those with concurrent CCF/CRF/HT had significantly higher baseline NT-proBNP levels (1724.2 pg/mL versus 277.7 pg/mL, P = 0.03). The gene discussed is NPPB; the disease is clubfoot.