2014). In adeno‐myrAkt1 C2C12 myocytes, FGF21 concentration in both the cell lysate and the cell media is higher than the control (Izumiya et al. 2008). In addition, in a human experiment, serum and skeletal muscle FGF21 increased in response to acute hyperinsulinemia in healthy young men (Hojman et al. 2009). The gene discussed is FGF21; the disease is Hyperinsulinemia.