This phenotype is strikingly similar to what is observed in arteriosclerosis-prone mice treated with AngII for 4-8 weeks, in which such aneurysms are commonly found in the abdominal region and therefore characterized as abdominal aortic aneurysms (AAA) (Daugherty et al., 2000). The gene discussed is AGT; the disease is abdominal aortic aneurysm.