To determine whether this was also the case in mammalian cells, we investigated mCherry‐FIP200 translocation in HeLa cells and SH‐SY5Y neuroblastoma cells in which we depleted Rab1a by siRNA—we chose Rab1a because it had been shown to regulate autophagy in mammalian cells (Winslow et al, 2010; Mukhopadhyay et al, 2011) and because we had identified Rab1a as a potential binding partner of C9orf72 by yeast 2 hybrid (Y2H, Fig 6A). Here, RAB1A is linked to neuroblastoma.