Furthermore, several ALS/FTD genes, such as charged multivesicular body protein‐2B (CHMP2B), valosin‐containing protein (VCP), ubiquilin 2, p62 (sequestosome 1), optineurin, and TANK‐binding kinase (TBK1), are directly linked to autophagy. The gene discussed is TBK1; the disease is frontotemporal dementia.