MMP8 and colorectal cancer: While our study did not find an evidence of association of the examined polymorphisms and overall survival in colorectal cancer, we cannot rule out the possible replication of the prognostic associations of the polymorphisms shown in Table 3 (particularly, the MMP27_rs11225388, MMP27_rs11225389, MMP27_rs2846707, and MMP8_rs1236508 polymorphisms) and Table S9 in larger and more powered study cohorts.