HDAC1 and chronic myelogenous leukemia, BCR-ABL1 positive: Agreeing with the known functions, pathway annotations such as “epigenetic regulation of gene expression” (Reactome pathway, P = 2.87e-13), and “chronic myeloid leukemia” (KEGG pathway, P = 1.61e-08) are enriched among HDAC1 network neighbors (Fig. 7a).