In the in vivo xenograft tumor model,although we did not measure T-cell proliferation directly, we observed a dramaticincrease in total T cells in both tumor tissues and spleen following anti-B7-H1treatment, suggesting that B7-H1 controls total T-cell population locally (within thetumor microenvironment) and distantly (in the spleen). Here, CD274 is linked to neoplasm.