Compared to WT mice, infection of Ccr2−/− mice at bite sites resulted in similar increases in innate immune gene expression and neutrophil influx and demonstrated similar virus titers at 4 hpi but failed to elicit an influx of myeloid CD11b+Ly6Chi cells (Figures 7I, 7J, S7D, and S7E). This evidence concerns the gene ITGAM and infection.