Figure 5 shows cytoplasmic, perinuclear, and punctate signals in tumor cells, indicating BSP-MMP2, OPN-MMP3, and DMP1-MMP9 colocalization and interaction in pAdC (Figures 5A-5C) and BPH (Figures 5D-5F). The gene discussed is MMP9; the disease is benign prostatic hyperplasia.