MYH9 and sensorineural hearing loss disorder: We over-expressed four mutant forms of Drosophila myoII in Johnston’s organ that contain variants commonly found in individuals with MYH9-related disorders who have sensorineural hearing loss (Franke et al., 2007) (Figure 4—figure supplement 1A) and observed scolopidial detachment with variable penetrance in all variant forms of myoII (Figure 4A–E).