To investigate if activation of FLT3 regulates PP2A activity we stably transduced BaF3 cells with an empty vector (EV) or vectors containing the wildtype (WT) human FLT3 gene, or human AML-associated kinase domain mutations FLT3-D835V and D835Y, or FLT3 with an internal tandem duplication, FLT3-ITD. The gene discussed is FLT3; the disease is acute myeloid leukemia.