MYO1E and breast cancer: Since our lab has previously shown that MYO1E localizes to cell-cell junctions between kidney epithelial cells and interacts with the tight junction protein ZO-1 [28], and we have found that MYO1E localized to cell-cell junctions in mammary tumors (Figure 2), we examined the localization of the tight junction marker ZO-1 and the adherens junction markers E-cadherin and β-catenin in the mammary tumors.