The graph in Figure 2E represents the volume of the primary tumor relative to the tumor age, with the date of tumor detection designated as “week 1.” Primary tumors from MYO1E WT PyMT mice averaged 705 mm3 (+/− 196) at 9 weeks after the initial detection, compared to 1829 mm3 (+/− 741) in MYO1E KO PyMT mice. Here, MYO1E is linked to neoplasm.