MYO1E and neoplasm: Interestingly, analysis of the volume of primary tumors (the first palpable tumor for each mouse) showed that, following the initial detection, the volume of primary tumors in the MYO1E KO PyMT mice appeared to increase faster than in the MYO1E WT PyMT mice as determined via caliper measurements (Figure 2E), although the difference was not statistically significant.