We performed a multivariate analysis to evaluate possible factors influencing HIG2 expression, including age at diagnosis, gender, tumor grade and KPS (Karnofsky performance status), using the REMBRANDT (Repository of Molecular Brain Neoplasia Data) database of the National Cancer Institute (NCI; http://caintegrator-info.nci.nih.gov/rembrant). This evidence concerns the gene HILPDA and neoplasm.