The CareStartTM G6PD RDT showed a fair degree of agreement (89.8 %; Kc = 0.278, p < 0.001) and a substantial degree of agreement (95.8 %; Kc = 0.773, p < 0.001) with the reference method in detecting G6PD deficiency at cut-off values of ≤10 and ≤20 % of normal activity, respectively (Table 5). This evidence concerns the gene G6PD and G6PD deficiency.