Of note is the finding that for rs780093 in the GCKR locus, the allele associated with higher IGF‐I concentration was already known to be associated with elevated risk of type 2 diabetes (P = 3.7 × 10−6), as well as higher levels of fasting glucose, fasting insulin, and HOMA‐IR (all P < 2.0 × 10−4), lower 2‐h glucose levels (P = 1.7 × 10−6), increased height (P = 2.0 × 10−4), lower waist‐to‐hip ratio (P = 0.0003), and higher lumbar spine bone mineral density (P = 0.002). The gene discussed is INS; the disease is type 2 diabetes mellitus.