The results revealed that the overall survival probability of high group was significantly lower than those of the low group (P = 0.0027, Fig. 1d), the average survival time for SALL4 low expression group was 39.6 months, whereas the median survival time for SALL4 high expression group was only 18.3 months, indicating that SALL4 could serve as a potential prognostic marker for ESCC. The gene discussed is SALL4; the disease is esophageal squamous cell carcinoma.