Deng et al. recently found that SALL4 expression was correlated with the Ki67 and CA199 expression in Intrahepatic cholangiocarcinoma (ICC) [25], these two factors are markers for increased proliferation of cancer cells, which may explain why SALL4 influences the proliferation of ESCC cells. The gene discussed is MKI67; the disease is intrahepatic cholangiocarcinoma.