Using GRSGWAS, there was no significant evidence of heterogeneity of the effect size for knee osteoarthritis, bipolar disorder, schizophrenia, or SBP, while the heterogeneity test was statistically significant for psoriatic arthritis, IBD, Crohn disease, CAD, DBP, eGFRcr, serum albumin, and serum protein. Here, ALB is linked to osteoarthritis, knee.